NOLTREX™ is a synthetic implant based on three-dimensional polyacrylamide cross-linked polymer with silver ions added. It helps to alleviate the symptoms of osteoarthritis, such as mild or severe pain, joint stiffness.
NOLTREX™ MOLECULAR WEIGHT > 10 000 000 DALTON.
Composition:
Cross-linked
Polyacrylamide, %
4,0 ± 1,5
Polyacrylamide, %
4,0 ± 1,5
Phosphate buffer, %
0,07 ± 0,005
0,07 ± 0,005
Silver ions, %
0,0001 - 0,0025
0,0001 - 0,0025
Sodium chloride, %
0,0028 ± 0,0001
0,0028 ± 0,0001
A disposable syringe of NOLTREX™ contains 2.5 ml of gel to be administered into the joint cavity.
Unlike other products commonly used in intra-articular injections, NOLTREX™ does not contain hyaluronic acid or other substances susceptible to degradation under the influence of enzymes contained in the human body, which ensures its long presence in the injection site.
NOLTREX™ is a biocompatible material, that has neither immunogenic, nor antigenic properties, it does not cause allergic reaction due to its synthetic nature.
NOLTREX™ is not a pharmacological medication from a group of antibiotics or antimicrobial drugs, so it cannot be used as a primary therapeutic agent for bacterial arthritis.